Welcome to ChesterRep - the University of Chester's Online Research Repository

ChesterRep is the University of Chester's institutional repository and an online platform designed to collate, store, and aid discoverability of research carried out at the university to the wider research community

For more information about how to submit material to ChesterRep, see our ChesterRep guides here. You can also find out more about our editorial and open access policies here. Please note that you must be a member of the University of Chester in order to view these pages.

  • Characterisation of the Muscle Protein Synthetic Response to Resistance Exercise in Healthy Adults: A Systematic Review and Exploratory Meta-Analysis.

    Davies, Robert W; orcid: 0000-0002-2994-7762; Lynch, Arthur E; orcid: 0000-0002-6160-2166; Kumar, Uttam; orcid: 0009-0007-2348-3630; Jakeman, Philip M; orcid: 0000-0002-1199-080X (2024-04-30)
    Five electronic databases (PubMed (Medline), Web of Science, Embase, Sport Discus, and Cochrane Library) were searched for controlled trials that assessed the MPS response to RE in healthy, adult humans, postabsorptive state. Individual study and random-effects meta-analysis arewere used to inform the effects of RE and covariates on MPS. Results from 79 controlled trials with 237 participants were analysed. Analysis of the pooled effects revealed robust increases in MPS following RE (weighted mean difference (WMD): 0.032% h , 95% CI: [0.024, 0.041] % h ,  = 92%,  = 37, < 0.001). However, the magnitude of the increase in MPS was lower in older adults (>50 y: WMD: 0.015% h , 95% CI: [0.007, 0.022] % h ,  = 76%,  = 12, = 0.002) compared to younger adults (<35 y: WMD: 0.041% h , 95% CI: [0.030, 0.052] % h ,  = 88%,  = 25, < 0.001). Individual studies have reported that the temporal proximity of the RE, muscle group, muscle protein fraction, RE training experience, and the loading parameters of the RE (i.e., intensity, workload, and effort) appeared to affect the MPS response to RE, whereas sex or type of muscle contraction does not. A single bout of RE can sustain measurable increases in postabsorptive MPS soon after RE cessation and up to 48 h post-RE. However, there is substantial heterogeneity in the magnitude and time course of the MPS response between trials, which appears to be influenced by participants' age and/or the loading parameters of the RE itself. [Abstract copyright: Copyright © 2024 Robert W. Davies et al.]
  • Flexibility

    Izak, Michal; University of Chester (Edward Elgar Publishing, 2024-07-30)
    Importance and popularity of the concept of flexibility in the context of work is only matched by its lack of clarity. While it is clearly on the upward trajectory, both as an organizational practice and as a topic for discussions on academic and practitioner fora, it is yet riddled with paradoxes, used to denote different meanings and practices, and therefore confusion as regards flexibility at work is never far away. This entry intends to present the practical importance of flexibility at work, while also demonstrating the complex nature of discussions in which it is imbued and the divergent practices which it is used to designate. It also attempts to provide a critical reflection on the potential trajectory which could lead to alleviating the paradigmatic fractures between different flexibility clusters towards supporting a more seamless practical application and more coherent intellectual environment for exploring it.
  • Social media: helpful or harmful?

    Reeves, Andrew; University of Chester (BACP, 2024-04)
    In our digital age, many people spend a significant portion of their day online. In particular, social media has become a potent force in shaping our daily lives. Online platforms can offer positive opportunities for sharing thoughts, ideas and experiences, helping many to feel connected to one another. This article considers how mental health is navigated and understood through the lens of social media and explores the helpful and harmful aspects that can be encountered.
  • Internationalization of liquor in the age of social media: Navigating the digital silk road through netnography

    Fenton, Alex; Qian, Ann; University of Chester (Sichuan University of Science and Engineering, 2024-04)
    We presented Internationalization of baijiu in the age of social media: Navigating the digital silk road through netnography
  • A 12 week double-blind randomised controlled trial investigating the effect of dietary supplementation with 5000 IU/day (125 µg/day) vitamin D in adults with asthma

    Mushtaq, Sohail; Watkins, Stephanie; Harrison, Tanja; University of Chester (Cambridge University Press, 2024-05-16)
    Vitamin D deficiency has previously been linked to higher rates of exacerbation and reduced lung function in asthmatics. Previous randomised controlled trials (RCT) investigating the effect of vitamin D supplementation have mainly focussed on children with asthma. Trials involving adults have typically used bolus dosing regimes and the main outcomes have been patient focussed without investigating underlying inflammation. The present study aimed to conduct a 12-week placebo-controlled RCT administering a daily 5000 IU (125 µg) vitamin D3 supplement to adults with mild to moderate asthma. A total of 32 participants were randomised to receive either the 5000 IU vitamin D3 supplement or an identical matching placebo. The primary outcome of the study was lung function measured by ratio of FEV1:FVC (effect size 2.5) with secondary outcomes including asthma symptoms and inflammatory biomarkers. There was a small but statistically significant higher increase in the mean (± SD) ratio of FEV1: FVC from baseline to post-intervention in the vitamin D group (+ 0.05 ± 0.06) compared to the placebo group (+ 0.006 ± 0.04, p = 0.04). There was no effect of the intervention on asthma control test scores, or the inflammatory biomarkers measured. There was a moderate, significant association between baseline plasma 25(OH)D concentration and baseline plasma IL-10 (r = 0.527, p = 0.005) and TNF-α (r = -0.498. p = 0.008) concentrations. A daily vitamin D3 supplement led to slightly improved lung function in adult asthmatics and may be a useful adjunct to existing asthma control strategies, particularly for individuals with suboptimal vitamin D status.

View more