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dc.contributor.authorJohri, Nishant
dc.contributor.authorVengat, Maheshwari
dc.contributor.authorKumar, Deepanshu
dc.contributor.authorNagar, Priya
dc.contributor.authorJohn, Davis
dc.contributor.authorDutta, Shubham
dc.contributor.authorMittal, Piyush
dc.date.accessioned2023-11-30T02:46:43Z
dc.date.available2023-11-30T02:46:43Z
dc.date.issued2023-07-30
dc.identifierpubmed: 37975099
dc.identifierpmc: PMC10638272
dc.identifierdoi: 10.1007/s40200-023-01262-w
dc.identifierpii: 1262
dc.identifier.citationJohri, N., Vengat, M., Kumar, D., Nagar, P., John, D., Dutta, S., & Mittal, P. (2023). A comprehensive review on the risks assessment and treatment options for Sarcopenia in people with diabetes. Journal of Diabetes & Metabolic Disorders, 22(2), 995-1010. https://doi.org/10.1007/s40200-023-01262-w
dc.identifier.doi10.1007/s40200-023-01262-w
dc.identifier.urihttp://hdl.handle.net/10034/628316
dc.descriptionThis article is not available on ChesterRep
dc.description.abstractThis comprehensive review aims to examine the reciprocal interplay between Type 2 diabetes mellitus (T2DM) and sarcopenia, identify prevailing research gaps, and discuss therapeutic approaches and measures to enhance healthcare practices within hospital settings. A thorough literature review was conducted to gather relevant studies and articles on the relationship between T2DM and sarcopenia. Various databases were searched, including Google Scholar, PubMed, Scopus, and Science Direct databases. The search terms included T2DM, sarcopenia, inflammation, insulin resistance, advanced glycation end products, oxidative stress, muscle dimensions, muscle strength, muscle performance, aging, nutrition, hormone levels, and physical activity. The collected articles were critically analysed to extract key findings and identify gaps in current research. The prevalence and incidence of metabolic and musculoskeletal disorders, notably T2DM and sarcopenia, have surged in recent years. T2DM is marked by inflammation, insulin resistance, accumulation of advanced glycation end products, and oxidative stress, while sarcopenia involves a progressive decline in skeletal muscle mass and function. The review underscores the age-related correlation between sarcopenia and adverse outcomes like fractures, falls, and mortality. Research gaps regarding optimal nutritional interventions for individuals with T2DM and sarcopenia are identified, emphasizing the necessity for further investigation in this area. The reciprocal interplay between T2DM and sarcopenia holds significant importance. Further research is warranted to address knowledge gaps, particularly in utilizing precise measurement tools during clinical trials. Lifestyle modifications appear beneficial for individuals with T2DM and sarcopenia. Additionally, practical nutritional interventions require investigation to optimize healthcare practices in hospital settings. The online version contains supplementary material available at 10.1007/s40200-023-01262-w. [Abstract copyright: © The Author(s), under exclusive licence to Tehran University of Medical Sciences 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.]
dc.languageeng
dc.publisherSpringer Nature
dc.relation.urlhttps://link.springer.com/article/10.1007/s40200-023-01262-w
dc.sourcepissn: 2251-6581
dc.subjectT2DM
dc.subjectSarcopenia
dc.subjectObesity
dc.subjectHealth metabolic health
dc.subjectMuscle
dc.titleA comprehensive review on the risks assessment and treatment options for Sarcopenia in people with diabetes
dc.typeArticle
dc.identifier.eissn2251-6581
dc.contributor.departmentTeerthanker Mahaveer College of Pharmacy; University of Chester
dc.identifier.journalJournal of Diabetes & Metabolic Disorders
dc.date.updated2023-11-30T02:46:42Z
dc.date.accepted2023-07-03


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