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dc.contributor.authorChorley, Alan
dc.contributor.authorBott, Richard P.
dc.contributor.authorMarwood, Simon
dc.contributor.authorLamb, Kevin L.
dc.date.accessioned2021-12-21T09:21:01Z
dc.date.available2021-12-21T09:21:01Z
dc.date.issued2021-12-18
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/626587/EJAP%202021%20Accepted%20Copy.pdf?sequence=3
dc.identifier.citationChorley, A., Bott, R., Marwood, S., & Lamb, K.L. (2022). Bi-exponential modelling of W′ reconstitution kinetics in trained cyclists. European Journal of Applied Physiology, 122, 677–689. https://doi.org/10.1007/s00421-021-04874-3en_US
dc.identifier.issn1439-6319
dc.identifier.doi10.1007/s00421-021-04874-3
dc.identifier.urihttp://hdl.handle.net/10034/626587
dc.descriptionThis version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00421-021-04874-3en_US
dc.description.abstractPurpose The aim of this study was to investigate the individual W′ reconstitution kinetics of trained cyclists following repeated bouts of incremental ramp exercise, and to determine an optimal mathematical model to describe W′ reconstitution. Methods Ten trained cyclists (age 41 ± 10 years; mass 73.4 ± 9.9 kg; V˙O2max 58.6 ± 7.1 mL kg min−1) completed three incremental ramps (20 W min−1) to the limit of tolerance with varying recovery durations (15–360 s) on 5–9 occasions. W′ reconstitution was measured following the first and second recovery periods against which mono-exponential and bi-exponential models were compared with adjusted R2 and bias-corrected Akaike information criterion (AICc). Results A bi-exponential model outperformed the mono-exponential model of W′ reconstitution (AICc 30.2 versus 72.2), fitting group mean data well (adjR2 = 0.999) for the first recovery when optimised with parameters of fast component (FC) amplitude = 50.67%; slow component (SC) amplitude = 49.33%; time constant (τ)FC = 21.5 s; τSC = 388 s. Following the second recovery, W′ reconstitution reduced by 9.1 ± 7.3%, at 180 s and 8.2 ± 9.8% at 240 s resulting in an increase in the modelled τSC to 716 s with τFC unchanged. Individual bi-exponential models also fit well (adjR2 = 0.978 ± 0.017) with large individual parameter variations (FC amplitude 47.7 ± 17.8%; first recovery: (τ)FC = 22.0 ± 11.8 s; (τ)SC = 377 ± 100 s; second recovery: (τ)FC = 16.3.0 ± 6.6 s; (τ)SC = 549 ± 226 s). Conclusions W′ reconstitution kinetics were best described by a bi-exponential model consisting of distinct fast and slow phases. The amplitudes of the FC and SC remained unchanged with repeated bouts, with a slowing of W′ reconstitution confined to an increase in the time constant of the slow component.en_US
dc.publisherSpringeren_US
dc.relation.urlhttps://link.springer.com/article/10.1007%2Fs00421-021-04874-3en_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectcritical poweren_US
dc.subjectrecoveryen_US
dc.subjectW′en_US
dc.subjectModellingen_US
dc.subjectfatigueen_US
dc.titleBi-exponential modelling of W' reconstitution kinetics in trained cyclistsen_US
dc.typeArticleen_US
dc.identifier.eissn1439-6327en_US
dc.contributor.departmentUniversity of Chester; Liverpool Hope Universityen_US
dc.identifier.journalEuropean Journal of Applied Physiologyen_US
or.grant.openaccessYesen_US
rioxxterms.funderNoneen_US
rioxxterms.identifier.projectUnfundeden_US
rioxxterms.versionAMen_US
rioxxterms.versionofrecord10.1007/s00421-021-04874-3en_US
rioxxterms.licenseref.startdate2022-12-18
dcterms.dateAccepted2021-12-10
rioxxterms.publicationdate2021-12-18
dc.date.deposited2021-12-21en_US
dc.indentifier.issn1439-6319en_US


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