Show simple item record

dc.contributor.authorSemyanov, Alexey; email: semyanov@ibch.ru
dc.contributor.authorVerkhratsky, Alexei; email: alexej.verkhratsky@manchester.ac.uk
dc.date.accessioned2021-09-18T00:49:26Z
dc.date.available2021-09-18T00:49:26Z
dc.date.issued2021-08-06
dc.date.submitted2021-04-23
dc.identifierpubmed: 34479758
dc.identifierpii: S0166-2236(21)00143-0
dc.identifierdoi: 10.1016/j.tins.2021.07.006
dc.identifier.citationTrends in neurosciences
dc.identifier.urihttp://hdl.handle.net/10034/625884
dc.descriptionFrom PubMed via Jisc Publications Router
dc.descriptionHistory: received 2021-04-23, revised 2021-07-09, accepted 2021-07-20
dc.descriptionPublication status: aheadofprint
dc.description.abstractWe define a new concept of 'active milieu' that unifies all components of nervous tissue (neuronal and glial compartments, extracellular space, extracellular matrix, and vasculature) into a dynamic information processing system. Within this framework, we focus on the role of astrocytic processes, classified into organelle-containing branches and organelle-free leaflets. We argue that astrocytic branches with emanating leaflets are homologous to dendritic shafts with spines. Within the active milieu, astrocytic processes are engaged in reciprocal interactions with neuronal compartments and communication with other cellular and non-cellular elements of the nervous tissue. [Abstract copyright: Copyright © 2021 Elsevier Ltd. All rights reserved.]
dc.languageeng
dc.sourceeissn: 1878-108X
dc.subjectastrocytic branch
dc.subjectextrasynaptic signaling
dc.subjectastrocytic leaflet
dc.titleAstrocytic processes: from tripartite synapses to the active milieu.
dc.typearticle
dc.date.updated2021-09-18T00:49:26Z
dc.date.accepted2021-07-20


This item appears in the following Collection(s)

Show simple item record