Lifestyle-dependent microglial plasticity: training the brain guardians.
AuthorsAugusto-Oliveira, Marcus; orcid: 0000-0002-4772-9929; email: email@example.com
Verkhratsky, Alexei; orcid: 0000-0003-2592-9898; email: firstname.lastname@example.org
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AbstractLifestyle is one of the most powerful instruments shaping mankind; the lifestyle includes many aspects of interactions with the environment, from nourishment and education to physical activity and quality of sleep. All these factors taken in complex affect neuroplasticity and define brain performance and cognitive longevity. In particular, physical exercise, exposure to enriched environment and dieting act through complex modifications of microglial cells, which change their phenotype and modulate their functional activity thus translating lifestyle events into remodelling of brain homoeostasis and reshaping neural networks ultimately enhancing neuroprotection and cognitive longevity.
CitationBiology direct, volume 16, issue 1, page 12
DescriptionFrom Europe PMC via Jisc Publications Router
History: ppub 2021-08-01, epub 2021-08-05
Publication status: Published