Studying Effects of Calcium Oxide Nanoparticles on Dentinogenesis in Male Wistar Rats
AuthorsAl-Maula, Bushra Habeeb; orcid: 0000-0002-2293-4897; email: firstname.lastname@example.org
Wally, Zena Jehad; orcid: 0000-0002-0885-0179; email: email@example.com
Al-Magsoosi, Mohanad Jameel Najm; orcid: 0000-0002-9007-2870; email: firstname.lastname@example.org
Dosh, Rasha Hatem; orcid: 0000-0002-2318-6608; email: email@example.com
Mustafa, Ruba M.; orcid: 0000-0002-3425-459X; email: firstname.lastname@example.org
Al-Nasrawi, Suhad Jabbar Hamed; orcid: 0000-0003-3045-7389; email: email@example.com
Alfutimie, Abdullatif; orcid: 0000-0002-2531-3762; email: firstname.lastname@example.org
Haider, Julfikar; orcid: 0000-0001-7010-8285; email: email@example.com
MetadataShow full item record
AbstractThis study aimed to evaluate potential impacts of calcium oxide nanoparticles (CaO-NPs) at different dosages on predentin thickness, number of blood vessels, periodontal ligament thickness, and blood glucose level of Wistar rats. Twelve rats were randomly gathered into four groups, untreated (control) and CaO-NP-treated groups at three concentrations (25, 50, and 100 mg/kg of the body weight) over a period of 60 days. Histological investigation was performed on twenty-four lower incisor teeth extracted from all the tested groups under a light microscope, and an automatic Fujifilm was used to measure the blood glucose level. The results showed that regular nanoparticle treatment significantly increased predentin and periodontal ligament thicknesses, a gradual decrease in vascularization in the pulp tissue, and an increase in the blood glucose level as the dosages of nanoparticles administered to the rats increased. Administration of the CaO-NPs at low dosage (25 mg/kg) could be beneficial for the growth and integrity of teeth and dentinal tissues in rats.
CitationInternational Journal of Dentistry, volume 2021
DescriptionFrom Hindawi via Jisc Publications Router
History: publication-year 2021, received 2021-03-27, accepted 2021-07-18, pub-print 2021-07-26, archival-date 2021-07-26
Publication status: Published
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