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dc.contributor.authorShipton, Michael J.
dc.contributor.authorJohal, Nicholas J.
dc.contributor.authorDutta, Neel
dc.contributor.authorSlater, Christopher
dc.contributor.authorIqbal, Zohaib
dc.contributor.authorAhmed, Babur
dc.contributor.authorAmmori, Basil J.
dc.contributor.authorSenapati, Siba
dc.contributor.authorAkhtar, Khurshid
dc.contributor.authorSummers, Lucinda K. M.
dc.contributor.authorNew, John P.
dc.contributor.authorSoran, Handrean
dc.contributor.authorAdam, Safwaan
dc.contributor.authorSyed, Akheel A.; orcid: 0000-0001-8696-7121; email: akheel.syed@manchester.ac.uk
dc.date.accessioned2021-06-15T15:43:18Z
dc.date.available2021-06-15T15:43:18Z
dc.date.issued2020-09-01
dc.date.submitted2020-03-02
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/624952/11695_2020_Article_4943_nlm.xml?sequence=2
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/624952/11695_2020_Article_4943.pdf?sequence=3
dc.identifier.citationObesity Surgery, volume 31, issue 2, page 682-693
dc.identifier.urihttp://hdl.handle.net/10034/624952
dc.descriptionFrom Springer Nature via Jisc Publications Router
dc.descriptionHistory: received 2020-03-02, rev-recd 2020-08-17, accepted 2020-08-18, registration 2020-08-19, pub-electronic 2020-09-01, online 2020-09-01, pub-print 2021-02
dc.descriptionPublication status: Published
dc.descriptionFunder: University of Manchester
dc.description.abstractAbstract: Purpose: Bariatric surgery is associated with deficiencies of vitamins and minerals, and patients are routinely advised supplements postoperatively. We studied prevalence of vitamin B12, folate and iron deficiencies and anaemia before and after bariatric surgery over 4 years of follow-up. Materials and Methods: We performed a retrospective cohort analysis of 353 people with obesity, including 257 (72.8%) women, who underwent gastric bypass (252, 71.4%) or sleeve gastrectomy (101, 28.6%) at our National Health Service bariatric centre in Northwest England. Results: At baseline, mean (standard error) age was 46.0 (0.6) years, body mass index 53.1 (0.4) kg/m2, serum vitamin B12 400.2 (16.4) pg/L, folate 7.7 (0.2) μg/L, iron 12.0 (0.3) μmol/L, ferritin 118.3 (8.4) μg/L and haemoglobin 137.9 (0.8) g/L. Frequency of low vitamin B12 levels reduced from 7.5% preoperatively to 2.3% at 48 months (P < 0.038). Mean folate levels increased from baseline to 48 months by 5.3 μg/L (P < 0.001) but frequency of low folate levels increased from 4.7% preoperatively to 10.3% (P < 0.048). Ferritin levels increased from baseline to 48 months by 51.3 μg/L (P < 0.009). Frequency of low ferritin levels was greater in women (39.1%) than in men (8.9%) at baseline (P < 0.001) and throughout the study period. Haemoglobin was low in 4.6% of all patients at baseline with no significant change over the study period. Conclusion: There were notable rates of haematinic insufficiencies in bariatric surgical candidates preoperatively. Our study lends further support to regular supplementation with vitamin B12, folic acid, and iron in people undergoing bariatric surgery.
dc.languageen
dc.publisherSpringer US
dc.rightsLicence for this article: http://creativecommons.org/licenses/by/4.0/
dc.sourcepissn: 0960-8923
dc.sourceeissn: 1708-0428
dc.subjectOriginal Contributions
dc.subjectObesity
dc.subjectMorbid
dc.subjectGastric bypass
dc.subjectGastrectomy
dc.subjectAnaemia
dc.subjectIron deficiency
dc.subjectVitamin B12 deficiency
dc.subjectFolic acid deficiency
dc.titleHaemoglobin and Hematinic Status Before and After Bariatric Surgery over 4 years of Follow-Up
dc.typearticle
dc.date.updated2021-06-15T15:43:18Z
dc.date.accepted2020-08-18


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