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dc.contributor.authorHalls, Daniel
dc.contributor.authorLeslie, Monica
dc.contributor.authorLeppanen, Jenni
dc.contributor.authorSedgewick, Felicity
dc.contributor.authorSurguladze, Simon
dc.contributor.authorFonville, Leon
dc.contributor.authorLang, Katie
dc.contributor.authorSimic, Mima
dc.contributor.authorNicholls, Dasha
dc.contributor.authorWilliams, Steven
dc.contributor.authorTchanturia, Kate
dc.date.accessioned2021-03-24T11:40:54Z
dc.date.available2021-03-24T11:40:54Z
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/624393/figure1.pdf?sequence=2
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/624393/emotional_face_of_AN_submission_version%20%281%29.pdf?sequence=6
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/624393/Emotional_face_of_AN_supplementary_material.pdf?sequence=7
dc.identifier.citationHalls, D., Leslie, M., Leppanen, J., Sedgewick, F., Surguladze, S., Fonville, L., ... & Tchanturia, K. (2021). The emotional face of anorexia nervosa: The neural correlates of emotional processing. Human Brain Mapping.en_US
dc.identifier.urihttp://hdl.handle.net/10034/624393
dc.description.abstractSocial-emotional processing difficulties have been reported in Anorexia Nervosa (AN), yet the neural correlates remain unclear. Previous neuroimaging work is sparse and has not used functional connectivity paradigms to more fully explore the neural correlates of emotional difficulties. Fifty-seven acutely unwell AN (AAN) women, 60 weight-recovered AN (WR) women and 69 healthy control (HC) women categorised the gender of a series of emotional faces while undergoing Functional Magnetic Resonance Imaging. The mean age of the AAN group was 19.40 (2.83), WR 18.37 (3.59) and HC 19.37 (3.36). A whole brain and psychophysical interaction connectivity approach was used. Parameter estimates from significant clusters were extracted and correlated with clinical symptoms. Whilst no group level differences in whole brain activation were demonstrated, significant group level functional connectivity differences emerged. WR participants showed increased connectivity between the bilateral occipital face area and the cingulate, precentral gyri, superior, middle, medial and inferior frontal gyri compared to AAN and HC when viewing happy valenced faces. Eating disorder symptoms and parameter estimates were positively correlated. Our findings characterise the neural basis of social-emotional processing in a large sample of individuals with AN.en_US
dc.publisherWileyen_US
dc.relation.urlhttps://onlinelibrary.wiley.com/doi/10.1002/hbm.25417en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.subjectAnorexia nervosaen_US
dc.subjectEmotional processingen_US
dc.subjectEmotional facesen_US
dc.subjectFunctional magnetic resonance imagingen_US
dc.subjectPsychophysical interactionen_US
dc.titleThe Emotional Face of Anorexia Nervosa: The Neural Correlates of Emotional Processingen_US
dc.typeArticleen_US
dc.identifier.eissn1097-0193en_US
dc.contributor.departmentKing's College London; University of Chester; University of Bristol; Imperial College London; Maudsley NHS Foundation Trust; Illia State Universityen_US
dc.identifier.journalHuman Brain Mappingen_US
or.grant.openaccessYesen_US
rioxxterms.funderMedical Research Councilen_US
rioxxterms.identifier.projectNot applicableen_US
rioxxterms.versionAMen_US
rioxxterms.versionofrecord10.1002/hbm.25417en_US
rioxxterms.licenseref.startdate2021-03-19
dcterms.dateAccepted2021-03-08
rioxxterms.publicationdate2021-03-19
dc.date.deposited2021-03-24en_US
dc.indentifier.issn1065-9471en_US


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 International