Improved social functioning following social recovery therapy in first episode psychosis: Do social cognition and neurocognition change following therapy, and do they predict treatment response?
Authors
Griffiths, Siân Lowri; email: s.l.griffiths@bham.ac.ukWood, Stephen J
Fowler, David
Freemantle, Nick
Hodgekins, Joanne
Jones, Peter B
Singh, Swaran
Sharma, Vimal
Birchwood, Max
Publication Date
2021-01-21Submitted date
2020-01-11
Metadata
Show full item recordAbstract
There is a need to develop and refine psychosocial interventions to improve functioning in First Episode Psychosis (FEP). Social cognition and neurocognition are closely linked to functioning in psychosis; examinations of cognition pre- and post- psychosocial intervention may provide insights into the mechanisms of these interventions, and identify which individuals are most likely to benefit. Cognition was assessed within a multi-site trial of Social Recovery Therapy (SRT) for individuals with FEP experiencing poor functioning (<30 h weekly structured activity). Fifty-nine participants were randomly allocated to the therapy group (SRT + Early intervention), and 64 were allocated to treatment as usual group (TAU - early intervention care). Social cognition and neurocognition were assessed at baseline and 9 months; assessors were blind to group allocation. It was hypothesized that social cognition would improve following therapy, and those with better social cognition prior to therapy would benefit the most from SRT. There was no significant impact of SRT on individual neurocognitive or social cognitive variables, however, joint models addressing patterns of missingness demonstrate improvement across a number of cognitive outcomes following SRT. Further, regression analyses showed those who had better social cognition at baseline were most likely to benefit from the therapy (ß = 0.350; 95% CI = 0.830 to 8.891; p = .019). It is not clear if SRT impacts on social cognitive or neurocognitive function, however, SRT may be beneficial in those with better social cognition at baseline. [Abstract copyright: Copyright © 2021. Published by Elsevier B.V.]Citation
Schizophrenia research, volume 228, page 249-255Type
articleDescription
From PubMed via Jisc Publications RouterHistory: received 2020-01-11, revised 2020-06-26, accepted 2020-12-29
Publication status: aheadofprint