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dc.contributor.authorMushtaq, Sohail
dc.contributor.authorTurner, Emma
dc.date.accessioned2021-01-14T14:34:37Z
dc.date.available2021-01-14T14:34:37Z
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/624177/acute-and-chronic-effects-of-beetroot-supplementation-on-blood-pressure-and-arterial-stiffness-in-humans.pdf?sequence=1
dc.identifier.citationTurner, E., & Mushtaq, S. (2015). Acute and chronic effects of beetroot supplementation on blood pressure and arterial stiffness in humans. Proceedings of the Nutrition Society, 74(OCE1).en_US
dc.identifier.urihttp://hdl.handle.net/10034/624177
dc.descriptionThis article has been accepted for publication and will appear in a revised form, subsequent to peer review and/or editorial input by Cambridge University Press, in Proceedings of the Nutrition Society published by Cambridge University Press. Copyright The Authors 2015.en_US
dc.description.abstractDietary supplementation of beetroot juice, containing nitrate- a potent vasodilation agent, has been shown to be vasoprotective( 1 ), and dose dependent decreases in blood pressure (BP) have been previously demonstrated(2,3). To our knowledge there has been only one study investigating the effect of beetroot supplementation in humans on arterial stiffness, measured using pulsewave velocity (PWV) and, although there was no effect of supplementation on PWV, there was a significant reduction due to beetroot supplementation in acute diastolic BP (3hrs, P = 0·023)( 4 ). A double-blind, randomised, cross-over intervention trial was carried out in a cohort of 12 healthy male participants (mean age (SEM) = 43 (2·1) yrs, BMI = 27·8 (1·1) kg.m2) who underwent both beetroot juice and placebo supplementation for 14 days. The aim of the study was to assess the effect of 6·45 mmol of nitrate in a concentrated 70 ml beetroot drink (James White Ltd, Ipswich, UK) on systolic and diastolic BP, mean arterial pressure (MAP) and arterial stiffness (PWV, aortic augmentation index (Aix), brachial Aix) in humans. BP and arterial stiffness measurements weretaken using PWV (Arteriograph, TensioMed,Hungary). Measurements were taken intriplicate at baseline, 3 hours post-supplementation (either beetroot juice orplacebo) and post-intervention (day 15). This was followed by a 7-day washoutperiod before participants were transferred to the alternate supplement. Table 1 shows that there was no significant acute or short term effect of beetroot juice supplementation on the parameters measured when compared to placebo. However, there was a significant decrease in systolic BP (P = 0·009), diastolic BP (P = 0·035), MAP (P = 0·017), aortic and brachial AIX (P = 0·042 and 0·041 respectively), 3hours post beetroot supplementation. These results confirm previous findings( 4 ) that beetroot supplementation does not have an acute or short term effect on arterial stiffness measures. However, acute effects on arterial stiffness and BP within the beetroot juice supplementation group were observed. Further large scale studies on dietary nitrate supplementation and cardiovascular health are required to further assess efficacy.en_US
dc.publisherCambridge University Pressen_US
dc.relation.urlhttps://www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/acute-and-chronic-effects-of-beetroot-supplementation-on-blood-pressure-and-arterial-stiffness-in-humans/9CD56F4E00ED9B767D0CA2A7B1693DE5en_US
dc.rightsAttribution-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nd/4.0/en_US
dc.titleAcute and chronic effects of beetroot supplementation on blood pressure and arterial stiffness in humansen_US
dc.typeArticleen_US
dc.identifier.eissn1475-2719en_US
dc.contributor.departmentUniversity of Chesteren_US
dc.identifier.journalProceedings of the Nutrition societyen_US
or.grant.openaccessYesen_US
rioxxterms.funderunfundeden_US
rioxxterms.identifier.projectunfundeden_US
rioxxterms.versionCVoRen_US
rioxxterms.versionofrecord10.1017/S0029665115001275en_US
rioxxterms.licenseref.startdate2016-04-15
dcterms.dateAccepted2015-04-15
rioxxterms.publicationdate2015-04-15
dc.date.deposited2021-01-14en_US
dc.indentifier.issn0029-6651en_US


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Except where otherwise noted, this item's license is described as Attribution-NoDerivatives 4.0 International