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dc.contributor.authorKirwan, Richard; orcid: 0000-0003-4645-0077; email: r.p.kirwan@2018.ljmu.ac.uk
dc.contributor.authorMcCullough, Deaglan; orcid: 0000-0002-9882-9639
dc.contributor.authorButler, Tom; orcid: 0000-0003-0818-1566; email: t.butler@chester.ac.uk
dc.contributor.authorPerez de Heredia, Fatima; orcid: 0000-0002-2537-3327
dc.contributor.authorDavies, Ian G; orcid: 0000-0003-3722-8466
dc.contributor.authorStewart, Claire; orcid: 0000-0002-8104-4819
dc.date.accessioned2020-10-15T00:38:20Z
dc.date.available2020-10-01
dc.date.issued2020-10-01
dc.date.submitted2020-11-05
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/623861/Kirwan2020_Article_SarcopeniaDuringCOVID-19Lockdo.pdf?sequence=2
dc.identifier.citationKirwan, R., McCullough, D., Butler, T., Perez de Heredia, F., Davies, I. & Stewart, C. (2020). Sarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss. GeroScience. https://doi.org/10.1007/s11357-020-00272-3
dc.identifier.urihttp://hdl.handle.net/10034/623861
dc.descriptionFrom PubMed via Jisc Publications Router
dc.descriptionHistory: received 2020-06-25, accepted 2020-09-16
dc.descriptionPublication status: aheadofprint
dc.description.abstractThe COVID-19 pandemic is an extraordinary global emergency that has led to the implementation of unprecedented measures in order to stem the spread of the infection. Internationally, governments are enforcing measures such as travel bans, quarantine, isolation, and social distancing leading to an extended period of time at home. This has resulted in reductions in physical activity and changes in dietary intakes that have the potential to accelerate sarcopenia, a deterioration of muscle mass and function (more likely in older populations), as well as increases in body fat. These changes in body composition are associated with a number of chronic, lifestyle diseases including cardiovascular disease (CVD), diabetes, osteoporosis, frailty, cognitive decline, and depression. Furthermore, CVD, diabetes, and elevated body fat are associated with greater risk of COVID-19 infection and more severe symptomology, underscoring the importance of avoiding the development of such morbidities. Here we review mechanisms of sarcopenia and their relation to the current data on the effects of COVID-19 confinement on physical activity, dietary habits, sleep, and stress as well as extended bed rest due to COVID-19 hospitalization. The potential of these factors to lead to an increased likelihood of muscle loss and chronic disease will be discussed. By offering a number of home-based strategies including resistance exercise, higher protein intakes and supplementation, we can potentially guide public health authorities to avoid a lifestyle disease and rehabilitation crisis post-COVID-19. Such strategies may also serve as useful preventative measures for reducing the likelihood of sarcopenia in general and in the event of future periods of isolation.
dc.languageeng
dc.sourceeissn: 2509-2723
dc.subjectAppetite regulation
dc.subjectCOVID-19
dc.subjectInflammation
dc.subjectObesity
dc.subjectPhysical activity
dc.subjectSarcopenia
dc.titleSarcopenia during COVID-19 lockdown restrictions: long-term health effects of short-term muscle loss.
dc.typearticle
dc.date.updated2020-10-15T00:38:20Z
dc.date.accepted2020-09-16


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