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dc.contributor.advisorJohn, Nigel
dc.contributor.advisorPop, Serban
dc.contributor.authorHolland, Mark, I
dc.date.accessioned2020-06-04T09:18:58Z
dc.date.available2020-06-04T09:18:58Z
dc.date.issued2020-05
dc.identifierhttps://chesterrep.openrepository.com/bitstream/handle/10034/623466/MH-Thesis.pdf?sequence=1
dc.identifier.citationHolland, M, I. (2020). Interactive Three-Dimensional Simulation and Visualisation of Real Time Blood Flow in Vascular Networks (Doctoral thesis). University of Chester, UK.en_US
dc.identifier.urihttp://hdl.handle.net/10034/623466
dc.description.abstractOne of the challenges in cardiovascular disease management is the clinical decision-making process. When a clinician is dealing with complex and uncertain situations, the decision on whether or how to intervene is made based upon distinct information from diverse sources. There are several variables that can affect how the vascular system responds to treatment. These include: the extent of the damage and scarring, the efficiency of blood flow remodelling, and any associated pathology. Moreover, the effect of an intervention may lead to further unforeseen complications (e.g. another stenosis may be “hidden” further along the vessel). Currently, there is no tool for predicting or exploring such scenarios. This thesis explores the development of a highly adaptive real-time simulation of blood flow that considers patient specific data and clinician interaction. The simulation should model blood realistically, accurately, and through complex vascular networks in real-time. Developing robust flow scenarios that can be incorporated into the decision and planning medical tool set. The focus will be on specific regions of the anatomy, where accuracy is of the utmost importance and the flow can develop into specific patterns, with the aim of better understanding their condition and predicting factors of their future evolution. Results from the validation of the simulation showed promising comparisons with the literature and demonstrated a viability for clinical use.en_US
dc.language.isoenen_US
dc.publisherUniversity of Chesteren_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectReal-time simulationen_US
dc.subjectRobust flow scenariosen_US
dc.subjectPatient dataen_US
dc.titleInteractive Three-Dimensional Simulation and Visualisation of Real Time Blood Flow in Vascular Networksen_US
dc.typeThesis or dissertationen_US
dc.publisher.departmentUnviersity of Chesteren_US
dc.rights.embargodate2020-12-01
dc.type.qualificationnamePhDen_US
dc.rights.embargoreasonSix month embargoen_US
dc.type.qualificationlevelDoctoralen_US


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