Browsing Theses by Submit Date
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Interactive Three-Dimensional Simulation and Visualisation of Real Time Blood Flow in Vascular NetworksOne of the challenges in cardiovascular disease management is the clinical decision-making process. When a clinician is dealing with complex and uncertain situations, the decision on whether or how to intervene is made based upon distinct information from diverse sources. There are several variables that can affect how the vascular system responds to treatment. These include: the extent of the damage and scarring, the efficiency of blood flow remodelling, and any associated pathology. Moreover, the effect of an intervention may lead to further unforeseen complications (e.g. another stenosis may be “hidden” further along the vessel). Currently, there is no tool for predicting or exploring such scenarios. This thesis explores the development of a highly adaptive real-time simulation of blood flow that considers patient specific data and clinician interaction. The simulation should model blood realistically, accurately, and through complex vascular networks in real-time. Developing robust flow scenarios that can be incorporated into the decision and planning medical tool set. The focus will be on specific regions of the anatomy, where accuracy is of the utmost importance and the flow can develop into specific patterns, with the aim of better understanding their condition and predicting factors of their future evolution. Results from the validation of the simulation showed promising comparisons with the literature and demonstrated a viability for clinical use.
Factors for successful Agile collaboration between UX designers and software developers in a complex organisationUser Centred Design (UCD) and Agile Software Development (ASD) processes have been two extremely successful methods for software development in recent years. However, both have been repeatedly described as frequently putting contradictory demands on people working with the respective processes. The current research addresses this point by focussing on the crucial relationship between a User Experience (UX) designer and a software developer. In-depth interviews, an online survey, a contextual inquiry and a diary study are described from a sample of over 100 designers, developers and their stakeholders (managers) in a large media organisation exploring factors for success in Agile development cycles. The findings from the survey show that organisational separation is challenge for agile collaboration between the two roles and while designers and developers have similar levels of (moderately positive) satisfaction with Agile processes, there are differences between the two roles. While developers are happier with the wider teamwork but want more access to and close collaboration with designers, particularly in an environment set up for Agile practices, the designers’ concern was the quality of the wider teamwork. The respondent’s comments also identified that the two roles saw a close – and ideally co-located – cooperation as essential for improving communication, reducing inefficiencies, and avoiding bad products being released. These results reflected the findings from the in-depth interviews with stakeholders. In particular, it was perceived that co-located pairing helped understanding different role-dependent demands and skills, increased efficiency of prototyping and implementing changes, and enabling localised decision-making. However, organisational processes, the setup of work-environment, and managerial traditions meant that this close collaboration and localised decision-making was often not possible to maintain over extended periods. Despite this, the studies conducted between pairs of designers and developers, found that successful collaboration between designers and developers can be found in a complex organisational setting. From the analysis of the empirical studies, six contributing factors emerged that support this. These factors are 1) Close proximity, 2) Early and frequent communication, 3) Shared ideation and problem solving, 4) Crossover of knowledge and skills, 5) Co-creation and prototyping and 6) Making joint decisions. These factors are crucially determined and empowered by the support from the organisational setting and 3 teams where practitioners work. Specifically, by overcoming key challenges to enable integration between UCD and ASD and thus encouraging close collaboration between UX designers and software developers, these challenges are: 1) Organisational structure and team culture, 2) Location and environmental setup and 3) Decision-making. These challenges along with the six factors that enable successful Agile collaboration between designers and developers provide the main contributions of this research. These contributions can be applied within large complex organisations by adopting the suggested ‘Paired Collaboration Manifesto’ to improve the integration between UCD and ASD. Beyond this, more empirical studies can take place, further extending improvements to the collaborative practices between the design and development roles and their surrounding teams.
Exploration and Implementation of Augmented Reality for External Beam RadiotherapyWe have explored applications of Augmented Reality (AR) for external beam radiotherapy to assist with treatment planning, patient education, and treatment delivery. We created an AR development framework for applications in radiotherapy (RADiotherapy Augmented Reality, RAD-AR) for AR ready consumer electronics such as tablet computers and head mounted devices (HMD). We implemented in RAD-AR three tools to assist radiotherapy practitioners with: treatment plans evaluation, patient pre-treatment information/education, and treatment delivery. We estimated accuracy and precision of the patient setup tool and the underlying self-tracking technology, and fidelity of AR content geometric representation, on the Apple iPad tablet computer and the Microsoft HoloLens HMD. Results showed that the technology could already be applied for detection of large treatment setup errors, and could become applicable to other aspects of treatment delivery subject to technological improvements that can be expected in the near future. We performed user feedback studies of the patient education and the plan evaluation tools. Results indicated an overall positive user evaluation of AR technology compared to conventional tools for the radiotherapy elements implemented. We conclude that AR will become a useful tool in radiotherapy bringing real benefits for both clinicians and patients, contributing to successful treatment outcomes.