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dc.contributor.authorJohnston, Matthew*
dc.contributor.authorMcBride, Michael*
dc.contributor.authorDahiya, Divakar*
dc.contributor.authorOwusu-Apenten, Richard K.*
dc.contributor.authorNigam, Poonam S.*
dc.date.accessioned2019-02-18T15:23:43Z
dc.date.available2019-02-18T15:23:43Z
dc.date.issued2018-11-27
dc.identifier.citationJohnston, M., McBride, M., Dahiya, D., Owusu-Apenten, R., & Nigam, P. S. (2018). Antibacterial activity of Manuka honey and its components: An overview. AIMS Microbiology, 4(4), 655–664.
dc.identifier.doi10.3934/microbiol.2018.4.655
dc.identifier.urihttp://hdl.handle.net/10034/621887
dc.description.abstractThe importance of honey for medicinal purposes is well documented in some of the world’s oldest literature. Honey is well known and studied for its antimicrobial properties. The medicinal properties in honey originate from the floral source used by bees. Manuka honey is a dark monofloral honey rich in phenolic content, and currently it is gaining much attention for its antimicrobial activity. Researchers have found that honey is effective against a wide range of pathogens. The antibacterial potency of Manuka honey was found to be related to the Unique Manuka Factor (UMF) rating, which is correlated with the methylglyoxal and total phenols content. It is reported that different types of Manuka honey have differing effects and Gram-negative bacteria are more resistant than Gram-positive bacteria. Bacterial resistance to honey as antimicrobial agent has yet to be identified, possibly due to the presence of a complex mixture of methylglyoxal and other components. Honey is also reported to alter a bacterium’s shape and size through septal ring alteration, which affects cell morphology and growth. Research has shown that Manuka honey of different UMF values has medicinal properties of interest and it can be beneficial when used as a combination treatment with other antimicrobial agents
dc.language.isoenen
dc.publisherAIMS Pressen_US
dc.relation.urlhttp://www.aimspress.com/journal/microbiologyen_US
dc.rightsAttribution-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nd/4.0/en_US
dc.subjectManuka honeyen_US
dc.subjectinfectionen_US
dc.subjectbacteriaen_US
dc.subjectantibacterialen_US
dc.subjectUMFen_US
dc.subjectmethylglyoxalen_US
dc.subjectbacterial resistanceen_US
dc.titleAntibacterial activity of Manuka honey and its components: An overviewen_US
dc.typeArticleen_US
dc.identifier.eissn2471-1888
dc.contributor.departmentUniversity of Chester, University of Ulster
dc.identifier.journalAIMS Microbiologyen_US
dc.date.accepted2018-11-22
or.grant.openaccessYesen_US
rioxxterms.funderNAen_US
rioxxterms.identifier.projectNAen_US
rioxxterms.versionVoRen_US
rioxxterms.licenseref.startdate2018-11-27


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Except where otherwise noted, this item's license is described as Attribution-NoDerivatives 4.0 International