What is the effect of aerobic exercise intensity on cardiorespiratory fitness in those undergoing cardiac rehabilitation? A systematic review with meta-analysis.
AuthorsMitchell, Braden L; orcid: 0000-0002-8091-2549
Lock, Merilyn J.
Buckley, John P.
Eston, Roger G.
MetadataShow full item record
AbstractAssess the role of exercise intensity on changes in cardiorespiratory fitness (CRF) in patients with cardiac conditions attending exercise-based cardiac rehabilitation. Systematic review with meta-analysis. MEDLINE, Embase, CINAHL, SPORTDiscus, PsycINFO and Web of Science. Studies assessing change in CRF (reported as peak oxygen uptake; V̇O ) in patients post myocardial infarction and revascularisation, following exercise-based cardiac rehabilitation. Studies establishing V̇O via symptom-limited exercise test with ventilatory gas analysis and reported intensity of exercise during rehabilitation were included. Studies with mean ejection fraction <40% were excluded. 128 studies including 13 220 patients were included. Interventions were classified as moderate, moderate-to-vigorous or vigorous intensity based on published recommendations. Moderate and moderate-to-vigorous-intensity interventions were associated with a moderate increase in V̇O (standardised mean difference±95% CI=0.94±0.30 and 0.93±0.17, respectively), and vigorous-intensity exercise with a large increase (1.10±0.25). Moderate and vigorous-intensity interventions were associated with moderate improvements in V̇O (0.63±0.34 and 0.93±0.20, respectively), whereas moderate-to-vigorous-intensity interventions elicited a large effect (1.27±0.75). Large heterogeneity among studies was observed for all analyses. Subgroup analyses yielded statistically significant, but inconsistent, improvements in CRF. Engagement in exercise-based cardiac rehabilitation was associated with significant improvements in both absolute and relative V̇O . Although exercise of vigorous intensity produced the greatest pooled effect for change in relative V̇O , differences in pooled effects between intensities could not be considered clinically meaningful. Prospero CRD42016035638. [Abstract copyright: © Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ.]
CitationBritish journal of sports medicine
DescriptionFrom PubMed via Jisc Publications Router.
Publication status: aheadofprint
History: accepted 2018-07-17