Name:
Mc Auley et al 2017.pdf
Embargo:
2217-10-25
Size:
529.5Kb
Format:
PDF
Request:
Book Chapter
Affiliation
University of Chester, Edgehill UniversityPublication Date
2017-10-25
Metadata
Show full item recordAbstract
Mathematical models have played key roles in developing our understanding of aging. The first pioneering mathematical models evaluated aging from an evolutionary perspective, generating meaningful insights into why aging occurs and laid the foundations for our current understanding of aging. More recently mathematical models have been used to gain a deeper understanding of the intracellular mechanisms associated with intrinsic aging. This chapter will outline what mathematical modelling is, and the advantages it has over more conventional approaches used in biogerontology. The steps involved in assembling a model will also be described and the leading theoretical frameworks underpinning them will be outlined. Moreover, we discuss in detail a variety of aging focused mechanistic mathematical models which have been developed in recent years. The chapter concludes by challenging the community to develop a unified mechanistic mathematical model which can be used to examine aging in a more integrated fashion.Citation
Mc Auley, M., Morgan, A. & Mooney, K. (2017). The role of Mathematical Modelling in understanding Aging. In Ahmad, S. I. (ed.), Aging: Exploring a Complex Phenomenon. CRC Press.Publisher
CRC PressAdditional Links
https://www.crcpress.com/Aging-Exploring-a-Complex-Phenomenon/Ahmad/p/book/9781138196971Type
Book chapterLanguage
enISBN
9781138196971Collections
The following license files are associated with this item: