Vitamin D and cardiometabolic disease risk: A RCT and cross-sectional study
dc.contributor.advisor | Mushtaq, Sohail | |
dc.contributor.advisor | Hughes, Stephen F. | |
dc.contributor.author | Agbalalah, Tari | * |
dc.date.accessioned | 2017-08-22T15:25:51Z | |
dc.date.available | 2017-08-22T15:25:51Z | |
dc.date.issued | 2017-01-30 | |
dc.identifier.citation | Agbalalah, T. (2017). Vitamin D and cardiometabolic disease risk: A RCT and cross-sectional study (Doctoral Dissertation). University of Chester, United Kingdom. | |
dc.identifier.uri | http://hdl.handle.net/10034/620602 | |
dc.description.abstract | Given the strong evidence for a beneficial role of vitamin D in diabetes and CVD pathogenesis, and the prevalence of vitamin D deficiency, vitamin D supplementation has been advocated for the prevention of cardiometabolic disease. To provide information on the effects of 5,000IU (125µg) vitamin D3 on cardiometabolic risk, a double blind, RCT in a cohort of overweight and obese UK adult males with plasma 25(OH)D concentration < 75nmol/L for a duration of 8 weeks was conducted. To the best of my knowledge, this is the first RCT to investigate the effect of 5,000IU (125µg) vitamin D3 on cardiometabolic markers in vitamin D insufficient, non-hypertensive and non-diabetic overweight and obese adult males. | |
dc.language.iso | en | en |
dc.publisher | University of Chester | |
dc.subject | Vitamin D | en |
dc.subject | Cardiometabolic disease | en |
dc.title | Vitamin D and cardiometabolic disease risk: A RCT and cross-sectional study | en |
dc.type | Thesis or dissertation | en |
dc.rights.embargodate | 22/02/2018 | |
dc.type.qualificationname | PhD | en |
dc.rights.embargoreason | Recommended embargo period | en |
dc.type.qualificationlevel | Doctoral | en |
html.description.abstract | Given the strong evidence for a beneficial role of vitamin D in diabetes and CVD pathogenesis, and the prevalence of vitamin D deficiency, vitamin D supplementation has been advocated for the prevention of cardiometabolic disease. To provide information on the effects of 5,000IU (125µg) vitamin D3 on cardiometabolic risk, a double blind, RCT in a cohort of overweight and obese UK adult males with plasma 25(OH)D concentration < 75nmol/L for a duration of 8 weeks was conducted. To the best of my knowledge, this is the first RCT to investigate the effect of 5,000IU (125µg) vitamin D3 on cardiometabolic markers in vitamin D insufficient, non-hypertensive and non-diabetic overweight and obese adult males. | |
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