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dc.contributor.advisorMushtaq, Sohail
dc.contributor.advisorHughes, Stephen F.
dc.contributor.authorAgbalalah, Tari*
dc.date.accessioned2017-08-22T15:25:51Z
dc.date.available2017-08-22T15:25:51Z
dc.date.issued2017-01-30
dc.identifier.citationAgbalalah, T. (2017). Vitamin D and cardiometabolic disease risk: A RCT and cross-sectional study (Doctoral Dissertation). University of Chester, United Kingdom.
dc.identifier.urihttp://hdl.handle.net/10034/620602
dc.description.abstractGiven the strong evidence for a beneficial role of vitamin D in diabetes and CVD pathogenesis, and the prevalence of vitamin D deficiency, vitamin D supplementation has been advocated for the prevention of cardiometabolic disease. To provide information on the effects of 5,000IU (125µg) vitamin D3 on cardiometabolic risk, a double blind, RCT in a cohort of overweight and obese UK adult males with plasma 25(OH)D concentration < 75nmol/L for a duration of 8 weeks was conducted. To the best of my knowledge, this is the first RCT to investigate the effect of 5,000IU (125µg) vitamin D3 on cardiometabolic markers in vitamin D insufficient, non-hypertensive and non-diabetic overweight and obese adult males.
dc.language.isoenen
dc.publisherUniversity of Chester
dc.subjectVitamin Den
dc.subjectCardiometabolic diseaseen
dc.titleVitamin D and cardiometabolic disease risk: A RCT and cross-sectional studyen
dc.typeThesis or dissertationen
dc.rights.embargodate22/02/2018
dc.type.qualificationnamePhDen
dc.rights.embargoreasonRecommended embargo perioden
dc.type.qualificationlevelDoctoralen
html.description.abstractGiven the strong evidence for a beneficial role of vitamin D in diabetes and CVD pathogenesis, and the prevalence of vitamin D deficiency, vitamin D supplementation has been advocated for the prevention of cardiometabolic disease. To provide information on the effects of 5,000IU (125µg) vitamin D3 on cardiometabolic risk, a double blind, RCT in a cohort of overweight and obese UK adult males with plasma 25(OH)D concentration < 75nmol/L for a duration of 8 weeks was conducted. To the best of my knowledge, this is the first RCT to investigate the effect of 5,000IU (125µg) vitamin D3 on cardiometabolic markers in vitamin D insufficient, non-hypertensive and non-diabetic overweight and obese adult males.
dc.rights.usageThe full-text may be used and/or reproduced in any format or medium, without prior permission or charge, for personal research or study, educational, or not-for-profit purposes provided that: - A full bibliographic reference is made to the original source - A link is made to the metadata record in ChesterRep - The full-text is not changed in any way - The full-text must not be sold in any format or medium without the formal permission of the copyright holders. - For more information please email researchsupport.lis@chester.ac.uk


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