Browsing Faculty of Medicine, Dentistry and Life Sciences by Authors
Extraction, identification and biological activities of saponins in sea cucumber Pearsonothuria graeffeiKhattaba, Rafat A.; Elbandy, Mohamed; Lawrence, Andrew J.; Paget, Tim; Rae-Rho, Jung; Binnasera, Yaser S.; Alih, Imran; Taibah University; Suez Canal University; Jizan University; Alarish University; University of Chester; Sunderland University; Kunsan National University; Central University, New Delhi (Bentham Science, 2018-04-01)Secondary metabolism in marine organisms produced a diversity of biological important natural compounds which are unpresented in terrestrial species. Sea cucumbers belong to the invertebrate Echinodermata and are famous for their nutraceutical, medical and food values. They are known for possession triterpenoid glycosides (saponins) with various ecological roles. The current work aimed to separate, identify and test various biological activities (anti-bacterial, antifungal, antileishmanial and anticancer properties) of saponins produced by the holothurian Pearsonothuria graeffei from the Red Sea, Egypt.