Affiliation
University at Albany ; University of Chester ; Center for Medical Sciences, Albany, NYPublication Date
2015-02-19
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This review examines the causal investigation of preclinical development of childhood asthma using exposomic tools. We examine the current state of knowledge regarding early-life exposure to non-biogenic indoor air pollution and the developmental modulation of the immune system. We examine how metabolomics technologies could aid not only in the biomarker identification of a particular asthma phenotype, but also the mechanisms underlying the immunopathologic process. Within such a framework, we propose alternate components of exposomic investigation of asthma in which, the exposome represents a reiterative investigative process of targeted biomarker identification, validation through computational systems biology and physical sampling of environmental mediaCitation
Choi, H., Mc Auley, M. T., & Lawrence, D. A. (2015). Prenatal exposures and exposomics of asthma. AIMS Environmental Science, 2(1), 87-109.Publisher
AIMS PressJournal
AIMS Environmental ScienceAdditional Links
http://www.aimspress.com/aimses/ch/reader/view_abstract.aspx?file_no=Environ2014015&flag=1Type
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en_USae974a485f413a2113503eed53cd6c53
10.3934/environsci.2015.1.87
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