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    Homocysteine and cognitive decline in healthy elderly

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    Authors
    McCaddon, Andrew
    Hudson, Peter R.
    Davies, Gareth K.
    Hughes, Alan
    Williams, John H. H.
    Wilkinson, Clare
    Affiliation
    University of Wales College of Medicine ; Wrexham Maelor Hospital ; Wrexham Maelor Hospital ; Royal Alexandra Hospital, Paisley ; Chester College ; University of Wales College of Medicine
    Publication Date
    2001-09
    
    Metadata
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    Abstract
    Serum homocysteine is increased, and correlates inversely with cognitive scores, in Alzheimer's disease (AD), vascular dementia and "age-associated memory impairment". Elevated levels might signal accelerated cognitive decline, although this remains to be established. We therefore repeated Mini-Mental State Examinations, together with additional ADAS-Cog assessments, in 32 healthy elderly individuals to determine whether prior homocysteine levels predicted cognitive changes over a 5-year period.
    Citation
    Dementia and Geriatric Cognitive Disorders, 2001, 12(5), pp. 309-313
    Publisher
    Karger
    Journal
    Dementia and Geriatric Cognitive Disorders
    URI
    http://hdl.handle.net/10034/226331
    DOI
    10.1159/000051275
    Additional Links
    http://content.karger.com/ProdukteDB/produkte.asp?Aktion=JournalHome&ProduktNr=224226
    Type
    Article
    Language
    en
    Description
    This article is not available through ChesterRep.
    ISSN
    1421-9824
    1420-8008
    Sponsors
    This article was submitted to the RAE2008 for the University of Chester - Allied Health Professions and Studies.
    ae974a485f413a2113503eed53cd6c53
    10.1159/000051275
    Scopus Count
    Collections
    Biological Sciences

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