Loading...
Prenatal exposures and exposomics of asthma
Choi, Hyunok Mc Auley, Mark T. Lawrence, David A.
Choi, Hyunok
Mc Auley, Mark T.
Lawrence, David A.
Citations
Altmetric:
Advisors
Editors
Other Contributors
Affiliation
University at Albany ; University of Chester ; Center for Medical Sciences, Albany, NY
EPub Date
Publication Date
2015-02-19
Submitted Date
Collections
Files
Loading...
article
Adobe PDF, 832.22 KB
Other Titles
Abstract
This review examines the causal investigation of preclinical development of childhood asthma using exposomic tools. We examine the current state of knowledge regarding early-life exposure to non-biogenic indoor air pollution and the developmental modulation of the immune system. We examine how metabolomics technologies could aid not only in the biomarker identification of a particular asthma phenotype, but also the mechanisms underlying the immunopathologic process. Within such a framework, we propose alternate components of exposomic investigation of asthma in which, the exposome represents a reiterative investigative process of targeted biomarker identification, validation through computational systems biology and physical sampling of environmental media
Citation
Choi, H., Mc Auley, M. T., & Lawrence, D. A. (2015). Prenatal exposures and exposomics of asthma. AIMS Environmental Science, 2(1), 87-109.
Publisher
AIMS Press
Journal
AIMS Environmental Science
Research Unit
PubMed ID
PubMed Central ID
Type
Article
Language
en_US