Stress, cortisol and central obesity in middle aged adults

Hdl Handle:
http://hdl.handle.net/10034/558302
Title:
Stress, cortisol and central obesity in middle aged adults
Authors:
Lasikiewicz, Nicola; Hendrickx, Hilde; Talbot, Duncan; Dye, Louise
Abstract:
Introduction: Obesity is associated with various psychological and physiological disturbances. Of interest is the relationship between central obesity and psychological stress. Central obesity is characterised by increased adipose tissue, often associated with glucocorticoid excess, specifically, the stress hormone cortisol. Consequently, a disturbed cortisol basal diurnal rhythm and impaired responses to psychological stress in middle aged adults with central obesity may be observed. Method: In study one, basal diurnal cortisol profiles were examined (n=147; mean = 46.21 ± 7.18 years) in a sample of high and low waist-hip ratio (WHR) males and females. Profiles were explored in terms of the area under the curve (AUC) of the cortisol-awakening response and diurnal decline. In study two, cortisol responses to a psychological stressor versus no-stress control (n=66; mean = 46 ± 7.17 years) in a sample of high and low WHR individuals were explored. Results: Blunted cortisol profiles, characterised by a reduced AUC, were observed in the majority (78%) of a middle-aged sample and were associated with significantly greater WHR. Further, blunted cortisol profiles were associated with a less favourable metabolic profile. When exposed to a psychological stressor, high WHR individuals, specifically males, tended to secrete greater cortisol. Conclusion: The findings suggest that central obesity is associated with altered cortisol responsivity. This highlights the vulnerability of high WHR individuals to stress related illness and disease. Further research, however, is required to elucidate whether stress exposure increases the propensity for central obesity or whether central obesity elevates stress responsivity.
Affiliation:
University of Chester
Citation:
Lasikiewicz, N. Hendrickx, H. Talbot, D. and Dye, L. (May 2013) Stress, cortisol and central obesity in middle aged adults. Paper presented at European Congress on Obesity (ECO2013), Liverpool, United Kingdom.
Publisher:
Karger
Journal:
Obesity Facts
Publication Date:
May-2013
URI:
http://hdl.handle.net/10034/558302
Type:
Meetings and Proceedings
Language:
en
ISBN:
9783318024500
Appears in Collections:
Psychology

Full metadata record

DC FieldValue Language
dc.contributor.authorLasikiewicz, Nicolaen
dc.contributor.authorHendrickx, Hildeen
dc.contributor.authorTalbot, Duncanen
dc.contributor.authorDye, Louiseen
dc.date.accessioned2015-06-22T10:02:08Zen
dc.date.available2015-06-22T10:02:08Zen
dc.date.issued2013-05en
dc.identifier.citationLasikiewicz, N. Hendrickx, H. Talbot, D. and Dye, L. (May 2013) Stress, cortisol and central obesity in middle aged adults. Paper presented at European Congress on Obesity (ECO2013), Liverpool, United Kingdom.en
dc.identifier.isbn9783318024500en
dc.identifier.urihttp://hdl.handle.net/10034/558302en
dc.description.abstractIntroduction: Obesity is associated with various psychological and physiological disturbances. Of interest is the relationship between central obesity and psychological stress. Central obesity is characterised by increased adipose tissue, often associated with glucocorticoid excess, specifically, the stress hormone cortisol. Consequently, a disturbed cortisol basal diurnal rhythm and impaired responses to psychological stress in middle aged adults with central obesity may be observed. Method: In study one, basal diurnal cortisol profiles were examined (n=147; mean = 46.21 ± 7.18 years) in a sample of high and low waist-hip ratio (WHR) males and females. Profiles were explored in terms of the area under the curve (AUC) of the cortisol-awakening response and diurnal decline. In study two, cortisol responses to a psychological stressor versus no-stress control (n=66; mean = 46 ± 7.17 years) in a sample of high and low WHR individuals were explored. Results: Blunted cortisol profiles, characterised by a reduced AUC, were observed in the majority (78%) of a middle-aged sample and were associated with significantly greater WHR. Further, blunted cortisol profiles were associated with a less favourable metabolic profile. When exposed to a psychological stressor, high WHR individuals, specifically males, tended to secrete greater cortisol. Conclusion: The findings suggest that central obesity is associated with altered cortisol responsivity. This highlights the vulnerability of high WHR individuals to stress related illness and disease. Further research, however, is required to elucidate whether stress exposure increases the propensity for central obesity or whether central obesity elevates stress responsivity.en
dc.language.isoenen
dc.publisherKargeren
dc.subjectObesityen
dc.subjectStressen
dc.titleStress, cortisol and central obesity in middle aged adultsen
dc.typeMeetings and Proceedingsen
dc.contributor.departmentUniversity of Chesteren
dc.identifier.journalObesity Factsen
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