Hdl Handle:
http://hdl.handle.net/10034/226331
Title:
Homocysteine and cognitive decline in healthy elderly
Authors:
McCaddon, Andrew; Hudson, Peter; Davies, Gareth; Hughes, Alan; Williams, John H H; Wilkinson, Clare
Abstract:
Serum homocysteine is increased, and correlates inversely with cognitive scores, in Alzheimer's disease (AD), vascular dementia and "age-associated memory impairment". Elevated levels might signal accelerated cognitive decline, although this remains to be established. We therefore repeated Mini-Mental State Examinations, together with additional ADAS-Cog assessments, in 32 healthy elderly individuals to determine whether prior homocysteine levels predicted cognitive changes over a 5-year period.
Affiliation:
University of Wales College of Medicine ; Wrexham Maelor Hospital ; Wrexham Maelor Hospital ; Royal Alexandra Hospital, Paisley ; Chester College ; University of Wales College of Medicine
Citation:
Dementia and Geriatric Cognitive Disorders, 2001, 12(5), pp. 309-313
Publisher:
Karger
Journal:
Dementia and Geriatric Cognitive Disorders
Issue Date:
Sep-2001
URI:
http://hdl.handle.net/10034/226331
DOI:
10.1159/000051275
Additional Links:
http://content.karger.com/ProdukteDB/produkte.asp?Aktion=JournalHome&ProduktNr=224226
Type:
Article
Language:
en
Description:
This article is not available through ChesterRep.
ISSN:
1421-9824; 1420-8008
Sponsors:
This article was submitted to the RAE2008 for the University of Chester - Allied Health Professions and Studies.
Appears in Collections:
Biological Sciences

Full metadata record

DC FieldValueLanguage
dc.contributor.authorMcCaddon, Andrewen_GB
dc.contributor.authorHudson, Peteren_GB
dc.contributor.authorDavies, Garethen_GB
dc.contributor.authorHughes, Alanen_GB
dc.contributor.authorWilliams, John H Hen_GB
dc.contributor.authorWilkinson, Clareen_GB
dc.date.accessioned2012-05-29T08:02:45Z-
dc.date.available2012-05-29T08:02:45Z-
dc.date.issued2001-09-
dc.identifier.citationDementia and Geriatric Cognitive Disorders, 2001, 12(5), pp. 309-313en_GB
dc.identifier.issn1421-9824-
dc.identifier.issn1420-8008-
dc.identifier.doi10.1159/000051275-
dc.identifier.urihttp://hdl.handle.net/10034/226331-
dc.descriptionThis article is not available through ChesterRep.en_GB
dc.description.abstractSerum homocysteine is increased, and correlates inversely with cognitive scores, in Alzheimer's disease (AD), vascular dementia and "age-associated memory impairment". Elevated levels might signal accelerated cognitive decline, although this remains to be established. We therefore repeated Mini-Mental State Examinations, together with additional ADAS-Cog assessments, in 32 healthy elderly individuals to determine whether prior homocysteine levels predicted cognitive changes over a 5-year period.en_GB
dc.description.sponsorshipThis article was submitted to the RAE2008 for the University of Chester - Allied Health Professions and Studies.en_GB
dc.language.isoenen
dc.publisherKargeren_GB
dc.relation.urlhttp://content.karger.com/ProdukteDB/produkte.asp?Aktion=JournalHome&ProduktNr=224226en_GB
dc.rightsArchived with thanks to Dementia and Geriatric Cognitive Disordersen_GB
dc.subjecthomocysteineen_GB
dc.subjectcognitionen_GB
dc.subjectvitamin B12en_GB
dc.subjectfolateen_GB
dc.titleHomocysteine and cognitive decline in healthy elderlyen
dc.typeArticleen
dc.contributor.departmentUniversity of Wales College of Medicine ; Wrexham Maelor Hospital ; Wrexham Maelor Hospital ; Royal Alexandra Hospital, Paisley ; Chester College ; University of Wales College of Medicineen_GB
dc.identifier.journalDementia and Geriatric Cognitive Disordersen_GB
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